| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR11634.1 | EAR11783.1 | PI23P_00470 | PI23P_01225 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.909 |
| EAR11634.1 | EAR13215.1 | PI23P_00470 | PI23P_01937 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.871 |
| EAR11634.1 | EAR13932.1 | PI23P_00470 | PI23P_05522 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | Probable glyceraldehyde-3-phosphate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.451 |
| EAR11634.1 | eno | PI23P_00470 | PI23P_00475 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | Enolase 2-phosphoglycerate dehydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.406 |
| EAR11634.1 | mdh | PI23P_00470 | PI23P_01010 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.992 |
| EAR11634.1 | pckA | PI23P_00470 | PI23P_08870 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.899 |
| EAR11783.1 | EAR11634.1 | PI23P_01225 | PI23P_00470 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.909 |
| EAR11783.1 | EAR13138.1 | PI23P_01225 | PI23P_01552 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Hypothetical protein; COG1878 Predicted metal-dependent hydrolase. | 0.746 |
| EAR11783.1 | EAR13215.1 | PI23P_01225 | PI23P_01937 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.893 |
| EAR11783.1 | EAR13447.1 | PI23P_01225 | PI23P_03097 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.940 |
| EAR11783.1 | EAR13932.1 | PI23P_01225 | PI23P_05522 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Probable glyceraldehyde-3-phosphate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.409 |
| EAR11783.1 | mdh | PI23P_01225 | PI23P_01010 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.917 |
| EAR11783.1 | pckA | PI23P_01225 | PI23P_08870 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.894 |
| EAR13138.1 | EAR11783.1 | PI23P_01552 | PI23P_01225 | Hypothetical protein; COG1878 Predicted metal-dependent hydrolase. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.746 |
| EAR13138.1 | EAR13215.1 | PI23P_01552 | PI23P_01937 | Hypothetical protein; COG1878 Predicted metal-dependent hydrolase. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.841 |
| EAR13138.1 | mdh | PI23P_01552 | PI23P_01010 | Hypothetical protein; COG1878 Predicted metal-dependent hydrolase. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.841 |
| EAR13138.1 | pckA | PI23P_01552 | PI23P_08870 | Hypothetical protein; COG1878 Predicted metal-dependent hydrolase. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.841 |
| EAR13215.1 | EAR11634.1 | PI23P_01937 | PI23P_00470 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.871 |
| EAR13215.1 | EAR11783.1 | PI23P_01937 | PI23P_01225 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.893 |
| EAR13215.1 | EAR13138.1 | PI23P_01937 | PI23P_01552 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Hypothetical protein; COG1878 Predicted metal-dependent hydrolase. | 0.841 |