Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAR13234.1COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (306 aa)    
Predicted Functional Partners:
EAR13235.1
Hypothetical protein; COG1045 Serine acetyltransferase.
 
 0.998
cysS
COG0215 Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.932
EAR13240.1
COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.889
EAR13710.1
Putative Oxidoreductase, FAD-binding protein; COG3182 Uncharacterized iron-regulated membrane protein.
  
 
 0.838
thrA
Bifunctional aspartokinase I/homoserine dehydrogenase I; COG2021 Homoserine acetyltransferase.
  
 
 0.797
EAR13236.1
COG0633 Ferredoxin.
     
 0.753
EAR13241.1
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.738
EAR12379.1
D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.705
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
   
  0.645
EAR13342.1
Methionine gamma-lyase; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
   
  0.645
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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