| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR11573.1 | metK | PI23P_00165 | PI23P_02112 | Hypothetical protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.796 |
| EAR11830.1 | EAR13342.1 | PI23P_10872 | PI23P_02572 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; COG0620 Methionine synthase II (cobalamin-independent). | Methionine gamma-lyase; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.723 |
| EAR11830.1 | ahcY | PI23P_10872 | PI23P_05637 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; COG0620 Methionine synthase II (cobalamin-independent). | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.949 |
| EAR11830.1 | metK | PI23P_10872 | PI23P_02112 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; COG0620 Methionine synthase II (cobalamin-independent). | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.962 |
| EAR12181.1 | metK | PI23P_12627 | PI23P_02112 | dTDP-glucose 4,6-dehydratase; COG0451 Nucleoside-diphosphate-sugar epimerases. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.796 |
| EAR12840.1 | metK | PI23P_09440 | PI23P_02112 | Probable acrA1 protein; COG1087 UDP-glucose 4-epimerase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.796 |
| EAR13342.1 | EAR11830.1 | PI23P_02572 | PI23P_10872 | Methionine gamma-lyase; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; COG0620 Methionine synthase II (cobalamin-independent). | 0.723 |
| EAR13342.1 | ahcY | PI23P_02572 | PI23P_05637 | Methionine gamma-lyase; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.530 |
| EAR13342.1 | metK | PI23P_02572 | PI23P_02112 | Methionine gamma-lyase; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.903 |
| EAR13531.1 | metK | PI23P_03517 | PI23P_02112 | Dihydroflavonol 4-reductase; COG0451 Nucleoside-diphosphate-sugar epimerases. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.796 |
| EAR13729.1 | metK | PI23P_04507 | PI23P_02112 | Putative oxidoreductase protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.796 |
| ahcY | EAR11830.1 | PI23P_05637 | PI23P_10872 | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; COG0620 Methionine synthase II (cobalamin-independent). | 0.949 |
| ahcY | EAR13342.1 | PI23P_05637 | PI23P_02572 | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Methionine gamma-lyase; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.530 |
| ahcY | metK | PI23P_05637 | PI23P_02112 | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.761 |
| fcl | metK | PI23P_06535 | PI23P_02112 | GDP-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.796 |
| metK | EAR11573.1 | PI23P_02112 | PI23P_00165 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Hypothetical protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | 0.796 |
| metK | EAR11830.1 | PI23P_02112 | PI23P_10872 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; COG0620 Methionine synthase II (cobalamin-independent). | 0.962 |
| metK | EAR12181.1 | PI23P_02112 | PI23P_12627 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | dTDP-glucose 4,6-dehydratase; COG0451 Nucleoside-diphosphate-sugar epimerases. | 0.796 |
| metK | EAR12840.1 | PI23P_02112 | PI23P_09440 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Probable acrA1 protein; COG1087 UDP-glucose 4-epimerase. | 0.796 |
| metK | EAR13342.1 | PI23P_02112 | PI23P_02572 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Methionine gamma-lyase; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.903 |