Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAR13268.1COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains. (407 aa)    
Predicted Functional Partners:
EAR12891.1
FixL-related histidine kinase; COG2202 FOG: PAS/PAC domain.
 
 0.919
EAR12648.1
Sensory transduction histidine kinase; COG0784 FOG: CheY-like receiver.
  
 0.899
EAR13293.1
Sensory box sensor histidine kinase; COG0784 FOG: CheY-like receiver.
 
 
 0.886
EAR13889.1
COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog.
 
  
 0.836
EAR13991.1
COG0642 Signal transduction histidine kinase.
   
 0.676
EAR12649.1
Sensory transduction histidine kinase; COG2202 FOG: PAS/PAC domain.
   
 0.676
miaB
tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
       0.639
EAR13269.1
Hypothetical protein.
       0.601
ribB
Putative riboflavin biosynthesis protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
  0.570
EAR13270.1
Hypothetical protein.
       0.558
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.