| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR11565.1 | EAR12106.1 | PI23P_00125 | PI23P_12252 | Riboflavin biosynthesis protein ribD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.472 |
| EAR11565.1 | EAR13359.1 | PI23P_00125 | PI23P_02657 | Riboflavin biosynthesis protein ribD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Putative NH(3)-dependent NAD+ synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.473 |
| EAR11565.1 | nadD | PI23P_00125 | PI23P_04747 | Riboflavin biosynthesis protein ribD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.646 |
| EAR12106.1 | EAR11565.1 | PI23P_12252 | PI23P_00125 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Riboflavin biosynthesis protein ribD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.472 |
| EAR12106.1 | EAR12696.1 | PI23P_12252 | PI23P_08720 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Putative competence-damage inducible; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.819 |
| EAR12106.1 | EAR13359.1 | PI23P_12252 | PI23P_02657 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Putative NH(3)-dependent NAD+ synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.541 |
| EAR12106.1 | EAR13952.1 | PI23P_12252 | PI23P_05622 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Possible transcriptional regulatory protein nadr; Probably asnc-family; COG3172 Predicted ATPase/kinase involved in NAD metabolism. | 0.697 |
| EAR12106.1 | nadD | PI23P_12252 | PI23P_04747 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.949 |
| EAR12696.1 | EAR12106.1 | PI23P_08720 | PI23P_12252 | Putative competence-damage inducible; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.819 |
| EAR12696.1 | EAR13359.1 | PI23P_08720 | PI23P_02657 | Putative competence-damage inducible; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | Putative NH(3)-dependent NAD+ synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.672 |
| EAR12696.1 | EAR13952.1 | PI23P_08720 | PI23P_05622 | Putative competence-damage inducible; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | Possible transcriptional regulatory protein nadr; Probably asnc-family; COG3172 Predicted ATPase/kinase involved in NAD metabolism. | 0.676 |
| EAR12696.1 | cobB | PI23P_08720 | PI23P_11477 | Putative competence-damage inducible; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily. | 0.571 |
| EAR12696.1 | nadD | PI23P_08720 | PI23P_04747 | Putative competence-damage inducible; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.849 |
| EAR12696.1 | ppnK | PI23P_08720 | PI23P_01787 | Putative competence-damage inducible; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.524 |
| EAR13357.1 | EAR13358.1 | PI23P_02647 | PI23P_02652 | Hypothetical protein. | Hypothetical protein. | 0.873 |
| EAR13357.1 | EAR13359.1 | PI23P_02647 | PI23P_02657 | Hypothetical protein. | Putative NH(3)-dependent NAD+ synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.638 |
| EAR13358.1 | EAR13357.1 | PI23P_02652 | PI23P_02647 | Hypothetical protein. | Hypothetical protein. | 0.873 |
| EAR13358.1 | EAR13359.1 | PI23P_02652 | PI23P_02657 | Hypothetical protein. | Putative NH(3)-dependent NAD+ synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.638 |
| EAR13359.1 | EAR11565.1 | PI23P_02657 | PI23P_00125 | Putative NH(3)-dependent NAD+ synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Riboflavin biosynthesis protein ribD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.473 |
| EAR13359.1 | EAR12106.1 | PI23P_02657 | PI23P_12252 | Putative NH(3)-dependent NAD+ synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.541 |