| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR11565.1 | EAR12410.1 | PI23P_00125 | PI23P_07290 | Riboflavin biosynthesis protein ribD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Putative biotin--(acetyl-CoA carboxylase) synthetase; COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 0.431 |
| EAR11565.1 | EAR13503.1 | PI23P_00125 | PI23P_03377 | Riboflavin biosynthesis protein ribD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | 0.689 |
| EAR11565.1 | guaA | PI23P_00125 | PI23P_06720 | Riboflavin biosynthesis protein ribD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.586 |
| EAR11565.1 | tilS | PI23P_00125 | PI23P_01912 | Riboflavin biosynthesis protein ribD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Putative cell-cycle protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.431 |
| EAR11947.1 | EAR12410.1 | PI23P_11457 | PI23P_07290 | Putative ATPase/GTPase; COG0802 Predicted ATPase or kinase. | Putative biotin--(acetyl-CoA carboxylase) synthetase; COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 0.617 |
| EAR11947.1 | EAR13503.1 | PI23P_11457 | PI23P_03377 | Putative ATPase/GTPase; COG0802 Predicted ATPase or kinase. | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | 0.968 |
| EAR11947.1 | tsaD | PI23P_11457 | PI23P_00370 | Putative ATPase/GTPase; COG0802 Predicted ATPase or kinase. | Putative glycoprotease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.877 |
| EAR12410.1 | EAR11565.1 | PI23P_07290 | PI23P_00125 | Putative biotin--(acetyl-CoA carboxylase) synthetase; COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Riboflavin biosynthesis protein ribD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.431 |
| EAR12410.1 | EAR11947.1 | PI23P_07290 | PI23P_11457 | Putative biotin--(acetyl-CoA carboxylase) synthetase; COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Putative ATPase/GTPase; COG0802 Predicted ATPase or kinase. | 0.617 |
| EAR12410.1 | EAR13503.1 | PI23P_07290 | PI23P_03377 | Putative biotin--(acetyl-CoA carboxylase) synthetase; COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | 0.577 |
| EAR12821.1 | EAR13503.1 | PI23P_09345 | PI23P_03377 | Hypothetical protein; COG1466 DNA polymerase III, delta subunit. | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | 0.504 |
| EAR13503.1 | EAR11565.1 | PI23P_03377 | PI23P_00125 | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | Riboflavin biosynthesis protein ribD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.689 |
| EAR13503.1 | EAR11947.1 | PI23P_03377 | PI23P_11457 | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | Putative ATPase/GTPase; COG0802 Predicted ATPase or kinase. | 0.968 |
| EAR13503.1 | EAR12410.1 | PI23P_03377 | PI23P_07290 | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | Putative biotin--(acetyl-CoA carboxylase) synthetase; COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 0.577 |
| EAR13503.1 | EAR12821.1 | PI23P_03377 | PI23P_09345 | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | Hypothetical protein; COG1466 DNA polymerase III, delta subunit. | 0.504 |
| EAR13503.1 | EAR13504.1 | PI23P_03377 | PI23P_03382 | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | COG1538 Outer membrane protein. | 0.617 |
| EAR13503.1 | guaA | PI23P_03377 | PI23P_06720 | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.442 |
| EAR13503.1 | mfd | PI23P_03377 | PI23P_05177 | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.529 |
| EAR13503.1 | tilS | PI23P_03377 | PI23P_01912 | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | Putative cell-cycle protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.521 |
| EAR13503.1 | truA | PI23P_03377 | PI23P_01642 | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.544 |