Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAR13525.1COG1587 Uroporphyrinogen-III synthase. (248 aa)    
Predicted Functional Partners:
EAR12363.1
Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.965
EAR13239.1
uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase.
  
 
 0.891
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.891
EAR12364.1
COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
 0.810
EAR13526.1
Hypothetical protein.
       0.772
EAR12864.1
Hypothetical protein.
  
     0.766
EAR12674.1
Hypothetical protein.
  
     0.757
EAR11797.1
Putative auxin-regulated protein.
  
     0.745
EAR12299.1
COG1333 ResB protein required for cytochrome c biosynthesis.
  
    0.738
EAR12154.1
Hypothetical protein; COG0251 Putative translation initiation inhibitor, yjgF family.
  
     0.727
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.