Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAR13588.1COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)    
Predicted Functional Partners:
EAR12229.1
Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1.
  
 0.978
EAR13801.1
COG0388 Predicted amidohydrolase.
   
 
 0.898
EAR12377.1
COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain; Belongs to the GcvP family.
   
 
 0.894
EAR11634.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
   
 0.891
EAR13398.1
COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
   
 0.891
EAR13330.1
COG1012 NAD-dependent aldehyde dehydrogenases.
   
 0.888
EAR12480.1
Acetoin dehydrogenase (TPP-dependent) beta chain; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
  
 
 0.886
EAR11530.1
COG0174 Glutamine synthetase.
   
 
 0.884
EAR11531.1
Glutamine synthetase; COG3968 Uncharacterized protein related to glutamine synthetase.
     
 0.883
EAR12228.1
Glutamate synthase, NADH/NADPH, small subunit 1; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
 
 0.881
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
Server load: low (12%) [HD]