Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAR13801.1COG0388 Predicted amidohydrolase. (273 aa)    
Predicted Functional Partners:
EAR12229.1
Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1.
    
 0.934
EAR13588.1
COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.898
EAR11758.1
COG0436 Aspartate/tyrosine/aromatic aminotransferase.
  
 
  0.880
EAR12775.1
COG0436 Aspartate/tyrosine/aromatic aminotransferase.
  
 
  0.880
EAR12228.1
Glutamate synthase, NADH/NADPH, small subunit 1; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
  0.879
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 0.855
EAR11577.1
Isocitrate dehydrogenase, NADP; COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.
     
  0.841
EAR11634.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
     
  0.841
EAR13398.1
COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
     
  0.841
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
     
 0.841
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.