Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EAR13860.1Smf protein DNA processing chain A; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. (367 aa)    
Predicted Functional Partners:
EAR13275.1
Putative amidophosphoribosyl-transferase; COG1040 Predicted amidophosphoribosyltransferases.
 
 
 0.902
EAR13218.1
Magnesium chelatase subunit ChlI; COG0606 Predicted ATPase with chaperone activity.
 
 0.884
EAR11813.1
Competence protein; COG0658 Predicted membrane metal-binding protein.
 
  
 0.878
EAR13434.1
Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.
 
  
 0.714
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.706
EAR13861.1
Hypothetical protein.
       0.664
EAR13859.1
Hypothetical protein.
       0.592
EAR12491.1
COG1555 DNA uptake protein and related DNA-binding proteins.
 
  
 0.559
EAR12479.1
Hypothetical protein.
 
     0.534
pyrB
COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
      0.530
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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