Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa)    
Predicted Functional Partners:
EAR13916.1
COG0498 Threonine synthase.
 
 0.999
EAR13918.1
Putative aspartokinase I-homoserine dehydrogenase; COG0527 Aspartokinases.
 
 0.999
thrA
Bifunctional aspartokinase I/homoserine dehydrogenase I; COG2021 Homoserine acetyltransferase.
 
 0.998
EAR12929.1
COG0460 Homoserine dehydrogenase.
  
 0.949
EAR13144.1
COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.863
EAR12214.1
4-amino-4-deoxychorismate lyase, putative; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
  
 
 0.863
EAR13235.1
Hypothetical protein; COG1045 Serine acetyltransferase.
     
 0.859
EAR12393.1
COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.859
EAR13249.1
COG2873 O-acetylhomoserine sulfhydrylase.
    
  0.849
EAR12769.1
Cystathionine beta-synthase; COG0031 Cysteine synthase.
     
 0.849
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
Server load: low (18%) [HD]