Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EAR13959.1COG1956 GAF domain-containing protein. (156 aa)    
Predicted Functional Partners:
EAR13249.1
COG2873 O-acetylhomoserine sulfhydrylase.
     
  0.873
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
  0.873
EAR13342.1
Methionine gamma-lyase; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
     
  0.873
EAR11982.1
Hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
      0.755
EAR11830.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; COG0620 Methionine synthase II (cobalamin-independent).
     
  0.659
purH
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.
       0.498
EAR12891.1
FixL-related histidine kinase; COG2202 FOG: PAS/PAC domain.
    
 0.470
EAR11964.1
Sensory transduction histidine kinase; COG2202 FOG: PAS/PAC domain.
    
 0.462
EAR13958.1
Hypothetical protein.
       0.407
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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