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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR14003.1COG0789 Predicted transcriptional regulators. (109 aa)    
Predicted Functional Partners:
EAR12891.1
FixL-related histidine kinase; COG2202 FOG: PAS/PAC domain.
 
 
 0.878
EAR12229.1
Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1.
    
 0.803
EAR12648.1
Sensory transduction histidine kinase; COG0784 FOG: CheY-like receiver.
   
 0.803
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.745
EAR12154.1
Hypothetical protein; COG0251 Putative translation initiation inhibitor, yjgF family.
  
 
   0.734
EAR13673.1
COG1076 DnaJ-domain-containing proteins 1.
  
 
 0.702
rpoA
DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.701
EAR13305.1
Hypothetical protein; COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain.
  
 
 0.701
EAR12328.1
Hypothetical protein; COG2214 DnaJ-class molecular chaperone.
  
 
 0.701
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.701
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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