Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAR14003.1COG0789 Predicted transcriptional regulators. (109 aa)    
Predicted Functional Partners:
EAR12229.1
Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1.
     
 0.931
EAR12891.1
FixL-related histidine kinase; COG2202 FOG: PAS/PAC domain.
 
 
 0.809
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.752
EAR12648.1
Sensory transduction histidine kinase; COG0784 FOG: CheY-like receiver.
   
 0.693
EAR14002.1
Putative transmembrane peptidase; COG0739 Membrane proteins related to metalloendopeptidases.
 
     0.682
EAR13293.1
Sensory box sensor histidine kinase; COG0784 FOG: CheY-like receiver.
    
 0.611
EAR13496.1
COG0281 Malic enzyme.
    
 0.609
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
    
 0.602
ribB
Putative riboflavin biosynthesis protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
  0.599
EAR12154.1
Hypothetical protein; COG0251 Putative translation initiation inhibitor, yjgF family.
  
 
   0.595
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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