| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR11783.1 | EAR12229.1 | PI23P_01225 | PI23P_06385 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1. | 0.914 |
| EAR11783.1 | EAR12300.1 | PI23P_01225 | PI23P_06740 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.836 |
| EAR11783.1 | EAR12301.1 | PI23P_01225 | PI23P_06745 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.755 |
| EAR11783.1 | EAR13040.1 | PI23P_01225 | PI23P_10440 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | FAD linked oxidase-like protein; COG0277 FAD/FMN-containing dehydrogenases. | 0.610 |
| EAR11783.1 | EAR13764.1 | PI23P_01225 | PI23P_04682 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.546 |
| EAR11783.1 | EAR13791.1 | PI23P_01225 | PI23P_04817 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins. | 0.473 |
| EAR11783.1 | icmF | PI23P_01225 | PI23P_06216 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.769 |
| EAR12084.1 | EAR12229.1 | PI23P_12142 | PI23P_06385 | Transcriptional regulator, MerR family protein; COG0789 Predicted transcriptional regulators. | Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1. | 0.931 |
| EAR12084.1 | EAR12300.1 | PI23P_12142 | PI23P_06740 | Transcriptional regulator, MerR family protein; COG0789 Predicted transcriptional regulators. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.771 |
| EAR12084.1 | EAR13764.1 | PI23P_12142 | PI23P_04682 | Transcriptional regulator, MerR family protein; COG0789 Predicted transcriptional regulators. | Acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.424 |
| EAR12084.1 | icmF | PI23P_12142 | PI23P_06216 | Transcriptional regulator, MerR family protein; COG0789 Predicted transcriptional regulators. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.851 |
| EAR12229.1 | EAR11783.1 | PI23P_06385 | PI23P_01225 | Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.914 |
| EAR12229.1 | EAR12084.1 | PI23P_06385 | PI23P_12142 | Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1. | Transcriptional regulator, MerR family protein; COG0789 Predicted transcriptional regulators. | 0.931 |
| EAR12229.1 | EAR12300.1 | PI23P_06385 | PI23P_06740 | Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.898 |
| EAR12229.1 | EAR13040.1 | PI23P_06385 | PI23P_10440 | Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1. | FAD linked oxidase-like protein; COG0277 FAD/FMN-containing dehydrogenases. | 0.949 |
| EAR12229.1 | EAR13764.1 | PI23P_06385 | PI23P_04682 | Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1. | Acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.898 |
| EAR12229.1 | icmF | PI23P_06385 | PI23P_06216 | Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.902 |
| EAR12300.1 | EAR11783.1 | PI23P_06740 | PI23P_01225 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.836 |
| EAR12300.1 | EAR12084.1 | PI23P_06740 | PI23P_12142 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Transcriptional regulator, MerR family protein; COG0789 Predicted transcriptional regulators. | 0.771 |
| EAR12300.1 | EAR12229.1 | PI23P_06740 | PI23P_06385 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1. | 0.898 |
