close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR12361.1Transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (294 aa)    
Predicted Functional Partners:
EAR12360.1
Putative tRNA methyltransferase; COG0566 rRNA methylases.
       0.697
mraW
S-adenosyl-methyltransferase MraW.
  
     0.685
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
     0.629
EAR12229.1
Large subunit of NADH-dependent glutamate synthase; COG0067 Glutamate synthase domain 1.
    
  0.594
hemH-2
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
       0.574
EAR11558.1
lysM domain protein.
  
     0.535
rpoA
DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
   0.523
EAR11583.1
Hypothetical protein.
  
     0.517
EAR13587.1
Glutamate dehydrogenase.
  
     0.495
EAR12363.1
Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
       0.485
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
Server load: low (28%) [HD]