Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
kmoHypothetical protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (469 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
 0.999
EAR13138.1
Hypothetical protein; COG1878 Predicted metal-dependent hydrolase.
 
  
  0.933
EAR12384.1
Endoribonuclease L-PSP; COG0251 Putative translation initiation inhibitor, yjgF family.
 
    0.853
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.
 
     0.845
EAR12636.1
Amino acid adenylation; COG0001 Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.836
EAR12388.1
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold.
 
  
 0.800
EAR13792.1
COG3483 Tryptophan 2,3-dioxygenase (vermilion).
 
  
 0.753
EAR12385.1
Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
 
 
  0.736
EAR13339.1
COG2124 Cytochrome P450.
   
 0.725
EAR13819.1
Phenylacetate-CoA oxygenase/reductase, PaaK subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
     
 0.668
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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