Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAR12665.1Sodium iodide symporter; COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (628 aa)    
Predicted Functional Partners:
EAR12664.1
COG2120 Uncharacterized proteins, LmbE homologs.
 
     0.814
EAR12763.1
COG3876 Uncharacterized protein conserved in bacteria.
      0.814
EAR12648.1
Sensory transduction histidine kinase; COG0784 FOG: CheY-like receiver.
   
 
 0.798
EAR12666.1
COG0673 Predicted dehydrogenases and related proteins.
       0.789
EAR12183.1
Hypothetical protein.
  
     0.742
EAR12891.1
FixL-related histidine kinase; COG2202 FOG: PAS/PAC domain.
   
 
 0.686
EAR13662.1
Hypothetical protein.
  
     0.605
lon
ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
   
   0.475
EAR12790.1
Hypothetical protein.
  
     0.471
EAR11905.1
CpmD protein involved in carbapenem biosynthesis; COG0506 Proline dehydrogenase.
 
  
 0.421
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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