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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
EAR12807.1Hypothetical protein; COG1169 Isochorismate synthase. (320 aa)    
Predicted Functional Partners:
menD
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
 
 0.990
EAR11733.1
COG0512 Anthranilate/para-aminobenzoate synthases component II.
  
  
 0.963
EAR13349.1
Putative chorismate mutase; COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase.
 
 
 0.942
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.932
EAR11734.1
COG0147 Anthranilate/para-aminobenzoate synthases component I.
  
  
0.896
EAR13208.1
COG0147 Anthranilate/para-aminobenzoate synthases component I.
  
  
 0.889
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
  
 0.853
EAR11758.1
COG0436 Aspartate/tyrosine/aromatic aminotransferase.
    
  0.843
EAR12775.1
COG0436 Aspartate/tyrosine/aromatic aminotransferase.
    
  0.843
EAR13998.1
Phenylalanine-4-hydroxylase; COG3186 Phenylalanine-4-hydroxylase.
     
  0.841
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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