Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAR12829.1COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (361 aa)    
Predicted Functional Partners:
EAR12715.1
COG2176 DNA polymerase III, alpha subunit (gram-positive type).
    
 0.915
EAR13279.1
COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
 
  
0.898
EAR12821.1
Hypothetical protein; COG1466 DNA polymerase III, delta subunit.
 
  
 0.897
EAR12456.1
COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
 
  
0.893
EAR12663.1
DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]
    
 0.883
EAR13807.1
Putative DNA polymerase III, delta subunit; COG0470 ATPase involved in DNA replication.
    
 0.878
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 0.878
EAR11493.1
COG0587 DNA polymerase III, alpha subunit.
    
 0.757
EAR12830.1
Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
       0.711
EAR12863.1
COG0210 Superfamily I DNA and RNA helicases.
 
 
 0.620
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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