Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAR12852.1DNA topoisomerase IV subunit B; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit. (619 aa)    
Predicted Functional Partners:
EAR12853.1
COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit.
 
 
 0.997
gyrA
DNA gyrase A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
 0.988
EAR13393.1
Putative helicase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.
  
 
 0.861
truB
Putative tRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
 
 0.667
argS
COG0018 Arginyl-tRNA synthetase.
  
  
 0.602
EAR12854.1
Hypothetical protein.
       0.596
secF
Putative protein-export transmembrane SecDF protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
  
 0.580
EAR13621.1
Hypothetical protein; COG1196 Chromosome segregation ATPases.
   
 
 0.557
EAR12553.1
Putative lipoprotein.
   
 
 0.557
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.540
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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