Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAR12885.1Acylaminoacyl-peptidase; COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases. (679 aa)    
Predicted Functional Partners:
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
  0.556
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
     
  0.555
EAR12886.1
Hypothetical protein; COG0151 Phosphoribosylamine-glycine ligase.
       0.543
EAR13113.1
COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases.
  
     0.538
EAR12088.1
Hypothetical protein; COG2199 FOG: GGDEF domain.
  
     0.508
EAR12884.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
       0.483
EAR13090.1
Secreted protein containing N-terminal zinc-dependent carboxypeptidase related domain; COG2866 Predicted carboxypeptidase.
  
     0.467
EAR13331.1
Putative protease; Degrades oligopeptides; Belongs to the peptidase S41B family.
  
     0.447
EAR12742.1
COG0006 Xaa-Pro aminopeptidase.
  
     0.432
EAR12756.1
Secreted protein containing N-terminal zinc-dependent carboxypeptidase-related domain, putative; COG4886 Leucine-rich repeat (LRR) protein.
  
     0.428
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
Server load: low (14%) [HD]