Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAR11935.1COG0330 Membrane protease subunits, stomatin/prohibitin homologs. (284 aa)    
Predicted Functional Partners:
nqrA
Na(+)-translocating NADH-quinone reductase subunit A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
 
      0.699
ftsH
Putative transmembrane AAA-metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.677
EAR12991.1
Hypothetical protein; COG4667 Predicted esterase of the alpha-beta hydrolase superfamily.
  
     0.547
EAR11936.1
Hypothetical protein.
 
     0.505
EAR13944.1
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
   0.485
EAR11765.1
Peptidase, M16 family protein; COG0612 Predicted Zn-dependent peptidases.
   
  0.461
EAR13689.1
Putative metallopeptidase, M16 family protein; COG0612 Predicted Zn-dependent peptidases.
   
  0.461
EAR13690.1
Probable peptidase; COG0612 Predicted Zn-dependent peptidases.
   
  0.461
EAR12447.1
COG4877 Uncharacterized protein conserved in bacteria.
  
    0.455
EAR12481.1
Aminopeptidase N.
  
 
   0.437
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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