STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR12105.1Hypothetical protein; COG1357 Uncharacterized low-complexity proteins. (190 aa)    
Predicted Functional Partners:
EAR12104.1
Hypothetical protein; COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component.
       0.773
EAR12891.1
FixL-related histidine kinase; COG2202 FOG: PAS/PAC domain.
  
 0.677
EAR12106.1
COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
       0.658
EAR12107.1
Hypothetical protein.
       0.658
EAR12103.1
Ribonuclease BN; COG1295 Predicted membrane protein.
       0.648
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.647
EAR12852.1
DNA topoisomerase IV subunit B; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit.
   
 
 0.647
EAR13447.1
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.541
EAR13293.1
Sensory box sensor histidine kinase; COG0784 FOG: CheY-like receiver.
     
 0.524
rlmH
Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
       0.493
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.