STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR12106.1COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (285 aa)    
Predicted Functional Partners:
nadD
Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.956
EAR12935.1
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
  
 0.941
EAR12696.1
Putative competence-damage inducible; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family.
    
 0.928
surE-2
Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.885
EAR13952.1
Possible transcriptional regulatory protein nadr; Probably asnc-family; COG3172 Predicted ATPase/kinase involved in NAD metabolism.
     
 0.882
EAR12107.1
Hypothetical protein.
       0.773
EAR12104.1
Hypothetical protein; COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component.
       0.658
EAR12105.1
Hypothetical protein; COG1357 Uncharacterized low-complexity proteins.
       0.658
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
     0.652
EAR12103.1
Ribonuclease BN; COG1295 Predicted membrane protein.
       0.647
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.