STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFU67124.12-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (391 aa)    
Predicted Functional Partners:
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 0.998
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.997
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.977
AFU70289.1
4-amino-4-deoxychorismate lyase PabC.
 
 0.968
AFU69310.1
Branched-chain amino acid aminotransferase IlvE; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.962
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.947
AFU67139.1
Acetolactate synthase small subunit.
 
 
 0.947
AFU67140.1
Acetolactate synthase large subunit.
 
 
 0.935
AFU67178.1
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.922
AFU70003.1
Fused propionyl-CoA synthetase/acetyl-CoA synthetase.
  
 
 0.922
Your Current Organism:
Psychroflexus torquis
NCBI taxonomy Id: 313595
Other names: P. torquis ATCC 700755, Psychroflexus torquis ACAM 623, Psychroflexus torquis ATCC 700755, Psychroflexus torquis str. ATCC 700755, Psychroflexus torquis strain ATCC 700755
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