STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFU67235.1Lipid A biosynthesis lauroyl acyltransferase. (293 aa)    
Predicted Functional Partners:
AFU70196.1
3-deoxy-D-manno-octulosonic-acid transferase KdtA; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
  
 0.979
AFU70448.1
UDP-N-acetylglucosamine O-acyltransferase LpxA; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.818
AFU68548.1
lipid-A-disaccharide synthase LpxB; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.813
lpxK
Tetraacyldisaccharide 4'-kinase LpxB; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
  
 0.801
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
   
 0.793
fabZ
N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase LpxC; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
 
   
 0.757
AFU70446.1
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase LpxD; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
   
 0.712
AFU69348.1
D-arabinose 5-phosphate isomerase associated with LPS/capsule synthesis, KpsF/GutQ family; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.681
AFU67234.1
Membrane-associated serine protease, rhomboid superfamily.
       0.658
AFU68765.1
ADP-heptose:LPS heptosyltransferase RfaF.
 
   
 0.564
Your Current Organism:
Psychroflexus torquis
NCBI taxonomy Id: 313595
Other names: P. torquis ATCC 700755, Psychroflexus torquis ACAM 623, Psychroflexus torquis ATCC 700755, Psychroflexus torquis str. ATCC 700755, Psychroflexus torquis strain ATCC 700755
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.