EAR14505.1 protein (Robiginitalea biformata)

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

EAR14505.1

Putative secreted glycosyl hydrolase. (1133 aa)

Predicted Functional Partners:

EAR14795.1

0.923

EAR16323.1

0.914

EAR15213.1

0.757

EAR15211.1

0.749

EAR16615.1

0.747

EAR15210.1

0.735

EAR15209.1

0.725

EAR15214.1

0.699

EAR16074.1

0.684

EAR15163.1

0.671

Your Current Organism:

Robiginitalea biformata

NCBI taxonomy Id: 313596
Other names: R. biformata HTCC2501, Robiginitalea biformata HTCC2501, Robiginitalea biformata str. HTCC2501, Robiginitalea biformata strain HTCC2501

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EAR14505.1	EAR14795.1	RB2501_00476	RB2501_10732	Putative secreted glycosyl hydrolase.	Putative secreted glycosyl hydrolase.	0.923
EAR14505.1	EAR15163.1	RB2501_00476	RB2501_12572	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.671
EAR14505.1	EAR15209.1	RB2501_00476	RB2501_12814	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.725
EAR14505.1	EAR15210.1	RB2501_00476	RB2501_12819	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.735
EAR14505.1	EAR15211.1	RB2501_00476	RB2501_12824	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.749
EAR14505.1	EAR15213.1	RB2501_00476	RB2501_12834	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.757
EAR14505.1	EAR15214.1	RB2501_00476	RB2501_12839	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.699
EAR14505.1	EAR16074.1	RB2501_00476	RB2501_04230	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.684
EAR14505.1	EAR16323.1	RB2501_00476	RB2501_05475	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.914
EAR14505.1	EAR16615.1	RB2501_00476	RB2501_06935	Putative secreted glycosyl hydrolase.	Quinate/shikimate dehydrogenase, putative.	0.747
EAR14795.1	EAR14505.1	RB2501_10732	RB2501_00476	Putative secreted glycosyl hydrolase.	Putative secreted glycosyl hydrolase.	0.923
EAR14795.1	EAR15163.1	RB2501_10732	RB2501_12572	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.525
EAR14795.1	EAR15209.1	RB2501_10732	RB2501_12814	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.696
EAR14795.1	EAR15210.1	RB2501_10732	RB2501_12819	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.782
EAR14795.1	EAR15211.1	RB2501_10732	RB2501_12824	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.739
EAR14795.1	EAR15213.1	RB2501_10732	RB2501_12834	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.758
EAR14795.1	EAR15214.1	RB2501_10732	RB2501_12839	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.718
EAR14795.1	EAR16074.1	RB2501_10732	RB2501_04230	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.594
EAR14795.1	EAR16323.1	RB2501_10732	RB2501_05475	Putative secreted glycosyl hydrolase.	Hypothetical protein.	0.916
EAR14795.1	EAR16615.1	RB2501_10732	RB2501_06935	Putative secreted glycosyl hydrolase.	Quinate/shikimate dehydrogenase, putative.	0.711

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

38

average node degree:

6.91

avg. local clustering coefficient:

0.895

expected number of edges:

36

PPI enrichment p-value:

0.415

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051144

Propanediol catabolic process

3 of 6

2.21

1.42

0.0021

GO:0006066

Alcohol metabolic process

4 of 46

1.45

1.14

0.0021

GO:0044282

Small molecule catabolic process

4 of 114

1.06

0.6

0.0276

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016903

Oxidoreductase activity, acting on the aldehyde or oxo group of donors

4 of 15

1.94

1.91

0.00012

GO:0016620

Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

3 of 11

1.95

1.33

0.0025

GO:0030976

Thiamine pyrophosphate binding

2 of 4

2.21

0.87

0.0245

GO:0016491

Oxidoreductase activity

5 of 232

0.85

0.46

0.0438

GO:0003824

Catalytic activity

11 of 1565

0.36

0.27

0.0245

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031469

Bacterial microcompartment

4 of 40

1.51

1.33

0.00074

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:35494230

(2022) Bacteroides ovatus colonization influences the abundance of intestinal short chain fatty acids and neurotransmitters.

2 of 6

2.04

0.89

0.0216

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1463

Butanoate metabolism, and Propanoate metabolism

9 of 59

1.7

3.58

7.76e-12

CL:1465

Pyruvate metabolism, and Geraniol degradation

6 of 25

1.89

3.31

1.28e-08

CL:1469

Pyruvate ferredoxin/flavodoxin oxidoreductase, and Pyruvate:ferredoxin oxidoreductase core domain II

3 of 5

2.29

2.1

9.68e-05

CL:1557

Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA, and Aldehyde dehydrogenase family

3 of 12

1.91

1.58

0.00065

CL:1491

3-oxoacid CoA-transferase, and CoA carboxylase activity

3 of 12

1.91

1.58

0.00065

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

fpla00620

Pyruvate metabolism

9 of 50

1.77

4.13

2.46e-13

fpla00430

Taurine and hypotaurine metabolism

4 of 5

2.42

3.45

2.00e-07

fpla00650

Butanoate metabolism

5 of 39

1.62

2.21

1.80e-06

fpla00640

Propanoate metabolism

5 of 40

1.61

2.19

1.80e-06

fpla01120

Microbial metabolism in diverse environments

9 of 156

1.28

1.93

1.86e-09

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031469

Polyhedral organelle

5 of 40

1.61

1.87

2.53e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0012

Acyltransferase

3 of 22

1.65

0.99

0.0089

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF06130

Phosphate propanoyltransferase

3 of 3

2.51

1.97

0.00022

PF00171

Aldehyde dehydrogenase family

3 of 5

2.29

1.85

0.00031

PF17147

Pyruvate:ferredoxin oxidoreductase core domain II

2 of 2

2.51

1.12

0.0090

PF01855

Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg

2 of 2

2.51

1.12

0.0090

PF02775

Thiamine pyrophosphate enzyme, C-terminal TPP binding domain

2 of 5

2.12

0.92

0.0187

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR008300

Phosphate propanoyltransferase

3 of 3

2.51

1.77

0.00052

IPR016163

Aldehyde dehydrogenase, C-terminal

3 of 5

2.29

1.67

0.00072

IPR016161

Aldehyde/histidinol dehydrogenase

3 of 6

2.21

1.65

0.00072

IPR029061

Thiamin diphosphate-binding fold

3 of 10

1.99

1.4

0.0018

IPR033412

Pyruvate:ferredoxin oxidoreductase, core domain II

2 of 2

2.51

1.04

0.0124

(more ...)

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