Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (430 aa)    
Predicted Functional Partners:
kmo
Monooxygenase family protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
 
 0.994
EAR16799.1
Tryptophan 2,3-dioxygenase.
 
 
 0.990
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.
 
  
  0.980
katG
Fungal/archaeal/bacterial heme catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
  0.900
EAR16042.1
Hypothetical protein.
 
  
 0.855
EAR14824.1
Hypothetical polyketide cyclase.
 
  
 0.751
EAR17157.1
Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 
  
 0.690
EAR14257.1
Predicted acetyltransferase.
       0.634
EAR14255.1
Major facilitator superfamily MFS_1.
       0.607
EAR15580.1
Hypothetical protein.
 
     0.586
Your Current Organism:
Robiginitalea biformata
NCBI taxonomy Id: 313596
Other names: R. biformata HTCC2501, Robiginitalea biformata HTCC2501, Robiginitalea biformata str. HTCC2501, Robiginitalea biformata strain HTCC2501
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