| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR14329.1 | EAR15504.1 | RB2501_02855 | RB2501_14289 | UDP-N-acetylmuramate--L-alanine ligase. | FtsK/SpoIIIE family protein. | 0.448 |
| EAR14329.1 | murD | RB2501_02855 | RB2501_02870 | UDP-N-acetylmuramate--L-alanine ligase. | Putative UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.998 |
| EAR14329.1 | murF | RB2501_02855 | RB2501_09620 | UDP-N-acetylmuramate--L-alanine ligase. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.897 |
| EAR14329.1 | murI | RB2501_02855 | RB2501_03250 | UDP-N-acetylmuramate--L-alanine ligase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.511 |
| EAR14409.1 | EAR14412.1 | RB2501_03255 | RB2501_03270 | Cationic outer membrane protein OmpH. | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.533 |
| EAR14409.1 | murI | RB2501_03255 | RB2501_03250 | Cationic outer membrane protein OmpH. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.595 |
| EAR14412.1 | EAR14409.1 | RB2501_03270 | RB2501_03255 | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Cationic outer membrane protein OmpH. | 0.533 |
| EAR14412.1 | EAR14434.1 | RB2501_03270 | RB2501_00121 | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.534 |
| EAR14412.1 | murD | RB2501_03270 | RB2501_02870 | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Putative UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.545 |
| EAR14412.1 | murF | RB2501_03270 | RB2501_09620 | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.434 |
| EAR14412.1 | murI | RB2501_03270 | RB2501_03250 | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.521 |
| EAR14434.1 | EAR14412.1 | RB2501_00121 | RB2501_03270 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.534 |
| EAR14434.1 | murI | RB2501_00121 | RB2501_03250 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.910 |
| EAR14812.1 | EAR17100.1 | RB2501_10817 | RB2501_09360 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate synthase (ferredoxin). | 0.999 |
| EAR14812.1 | glsA | RB2501_10817 | RB2501_12102 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutaminase; Belongs to the glutaminase family. | 0.905 |
| EAR14812.1 | murI | RB2501_10817 | RB2501_03250 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.913 |
| EAR15504.1 | EAR14329.1 | RB2501_14289 | RB2501_02855 | FtsK/SpoIIIE family protein. | UDP-N-acetylmuramate--L-alanine ligase. | 0.448 |
| EAR15504.1 | murF | RB2501_14289 | RB2501_09620 | FtsK/SpoIIIE family protein. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.421 |
| EAR15504.1 | murI | RB2501_14289 | RB2501_03250 | FtsK/SpoIIIE family protein. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.713 |
| EAR17100.1 | EAR14812.1 | RB2501_09360 | RB2501_10817 | Glutamate synthase (ferredoxin). | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.999 |