node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAR14564.1 | EAR15755.1 | RB2501_00771 | RB2501_15544 | 8-amino-7-oxononanoate synthase. | 8-amino-7-oxononanoate synthase. | 0.767 |
EAR14564.1 | EAR16834.1 | RB2501_00771 | RB2501_08030 | 8-amino-7-oxononanoate synthase. | Putative adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.952 |
EAR14564.1 | bioD | RB2501_00771 | RB2501_08020 | 8-amino-7-oxononanoate synthase. | Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.689 |
EAR14564.1 | kbl | RB2501_00771 | RB2501_07495 | 8-amino-7-oxononanoate synthase. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.766 |
EAR15755.1 | EAR14564.1 | RB2501_15544 | RB2501_00771 | 8-amino-7-oxononanoate synthase. | 8-amino-7-oxononanoate synthase. | 0.767 |
EAR15755.1 | EAR15760.1 | RB2501_15544 | RB2501_15569 | 8-amino-7-oxononanoate synthase. | L-allo-threonine aldolase. | 0.905 |
EAR15755.1 | EAR15914.1 | RB2501_15544 | RB2501_03430 | 8-amino-7-oxononanoate synthase. | Malonyl CoA-acyl carrier protein transacylase. | 0.884 |
EAR15755.1 | EAR16757.1 | RB2501_15544 | RB2501_07645 | 8-amino-7-oxononanoate synthase. | Hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.900 |
EAR15755.1 | EAR16834.1 | RB2501_15544 | RB2501_08030 | 8-amino-7-oxononanoate synthase. | Putative adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.569 |
EAR15755.1 | bioD | RB2501_15544 | RB2501_08020 | 8-amino-7-oxononanoate synthase. | Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.692 |
EAR15755.1 | gcvP | RB2501_15544 | RB2501_09705 | 8-amino-7-oxononanoate synthase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.934 |
EAR15755.1 | glyA | RB2501_15544 | RB2501_15879 | 8-amino-7-oxononanoate synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.911 |
EAR15755.1 | kbl | RB2501_15544 | RB2501_07495 | 8-amino-7-oxononanoate synthase. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.921 |
EAR15760.1 | EAR15755.1 | RB2501_15569 | RB2501_15544 | L-allo-threonine aldolase. | 8-amino-7-oxononanoate synthase. | 0.905 |
EAR15760.1 | EAR16757.1 | RB2501_15569 | RB2501_07645 | L-allo-threonine aldolase. | Hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.905 |
EAR15760.1 | gcvP | RB2501_15569 | RB2501_09705 | L-allo-threonine aldolase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.951 |
EAR15760.1 | glyA | RB2501_15569 | RB2501_15879 | L-allo-threonine aldolase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.923 |
EAR15760.1 | kbl | RB2501_15569 | RB2501_07495 | L-allo-threonine aldolase. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.905 |
EAR15914.1 | EAR15755.1 | RB2501_03430 | RB2501_15544 | Malonyl CoA-acyl carrier protein transacylase. | 8-amino-7-oxononanoate synthase. | 0.884 |
EAR15914.1 | kbl | RB2501_03430 | RB2501_07495 | Malonyl CoA-acyl carrier protein transacylase. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.868 |