STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR16846.1Putative threonine dehydratase, catabolic. (324 aa)    
Predicted Functional Partners:
EAR14388.1
Bifunctional aspartokinase I/homeserine dehydrogenase I.
  
 
 0.870
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.866
EAR15531.1
Putative acetohydroxyacid synthase small subunit.
  
  
 0.772
EAR16844.1
Putative transmembrane CorC/HlyC family transporter associated protein.
       0.746
EAR16845.1
Hypothetical protein.
       0.746
EAR14062.1
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
  
 0.743
EAR15236.1
Aspartokinase/homoserine dehydrogenase.
  
 
 0.707
EAR17100.1
Glutamate synthase (ferredoxin).
  
 
 0.688
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.670
EAR16843.1
Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
    0.622
Your Current Organism:
Robiginitalea biformata
NCBI taxonomy Id: 313596
Other names: R. biformata HTCC2501, Robiginitalea biformata HTCC2501, Robiginitalea biformata str. HTCC2501, Robiginitalea biformata strain HTCC2501
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.