node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAR14181.1 | EAR14910.1 | RB2501_02105 | RB2501_11307 | Elongation factor Tu; Belongs to the SecE/SEC61-gamma family. | YajC. | 0.940 |
EAR14181.1 | EAR17021.1 | RB2501_02105 | RB2501_08965 | Elongation factor Tu; Belongs to the SecE/SEC61-gamma family. | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.997 |
EAR14181.1 | ffh | RB2501_02105 | RB2501_10075 | Elongation factor Tu; Belongs to the SecE/SEC61-gamma family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.975 |
EAR14181.1 | ftsY | RB2501_02105 | RB2501_01845 | Elongation factor Tu; Belongs to the SecE/SEC61-gamma family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.972 |
EAR14181.1 | secA | RB2501_02105 | RB2501_11667 | Elongation factor Tu; Belongs to the SecE/SEC61-gamma family. | Translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.981 |
EAR14181.1 | secD | RB2501_02105 | RB2501_10472 | Elongation factor Tu; Belongs to the SecE/SEC61-gamma family. | Protein-export membrane protein SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.999 |
EAR14181.1 | secY | RB2501_02105 | RB2501_09955 | Elongation factor Tu; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.997 |
EAR14181.1 | yidC | RB2501_02105 | RB2501_12537 | Elongation factor Tu; Belongs to the SecE/SEC61-gamma family. | Putative inner membrane protein translocase component YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.974 |
EAR14910.1 | EAR14181.1 | RB2501_11307 | RB2501_02105 | YajC. | Elongation factor Tu; Belongs to the SecE/SEC61-gamma family. | 0.940 |
EAR14910.1 | EAR17021.1 | RB2501_11307 | RB2501_08965 | YajC. | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.937 |
EAR14910.1 | ffh | RB2501_11307 | RB2501_10075 | YajC. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.930 |
EAR14910.1 | ftsY | RB2501_11307 | RB2501_01845 | YajC. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.948 |
EAR14910.1 | secA | RB2501_11307 | RB2501_11667 | YajC. | Translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.912 |
EAR14910.1 | secD | RB2501_11307 | RB2501_10472 | YajC. | Protein-export membrane protein SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.994 |
EAR14910.1 | secY | RB2501_11307 | RB2501_09955 | YajC. | Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.931 |
EAR14910.1 | yidC | RB2501_11307 | RB2501_12537 | YajC. | Putative inner membrane protein translocase component YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.955 |
EAR15966.1 | yidC | RB2501_03690 | RB2501_12537 | Cytochrome c oxidase subunit II. | Putative inner membrane protein translocase component YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.885 |
EAR17021.1 | EAR14181.1 | RB2501_08965 | RB2501_02105 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Elongation factor Tu; Belongs to the SecE/SEC61-gamma family. | 0.997 |
EAR17021.1 | EAR14910.1 | RB2501_08965 | RB2501_11307 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | YajC. | 0.937 |
EAR17021.1 | ffh | RB2501_08965 | RB2501_10075 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.958 |