node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAR00113.1 | EAR00284.1 | FB2170_00565 | FB2170_12721 | Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Cystathionine beta-synthase. | 0.902 |
EAR00113.1 | EAR00330.1 | FB2170_00565 | FB2170_12951 | Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.900 |
EAR00113.1 | EAR01284.1 | FB2170_00565 | FB2170_11206 | Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Hypothetical protein. | 0.803 |
EAR00113.1 | EAR02440.1 | FB2170_00565 | FB2170_04115 | Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Probable L-serine dehydratase, alpha chain. | 0.900 |
EAR00113.1 | glyA | FB2170_00565 | FB2170_13241 | Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
EAR00113.1 | ilvA | FB2170_00565 | FB2170_12281 | Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.901 |
EAR00113.1 | trpA | FB2170_00565 | FB2170_16311 | Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.900 |
EAR00113.1 | trpB | FB2170_00565 | FB2170_09386 | Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
EAR00113.1 | trpB-2 | FB2170_00565 | FB2170_16306 | Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
EAR00284.1 | EAR00113.1 | FB2170_12721 | FB2170_00565 | Cystathionine beta-synthase. | Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.902 |
EAR00284.1 | EAR00330.1 | FB2170_12721 | FB2170_12951 | Cystathionine beta-synthase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.907 |
EAR00284.1 | EAR00842.1 | FB2170_12721 | FB2170_17196 | Cystathionine beta-synthase. | Bifunctional aspartokinase I/homoserine dehydrogenase I. | 0.903 |
EAR00284.1 | EAR01284.1 | FB2170_12721 | FB2170_11206 | Cystathionine beta-synthase. | Hypothetical protein. | 0.962 |
EAR00284.1 | EAR02440.1 | FB2170_12721 | FB2170_04115 | Cystathionine beta-synthase. | Probable L-serine dehydratase, alpha chain. | 0.907 |
EAR00284.1 | glyA | FB2170_12721 | FB2170_13241 | Cystathionine beta-synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.921 |
EAR00284.1 | ilvA | FB2170_12721 | FB2170_12281 | Cystathionine beta-synthase. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.913 |
EAR00284.1 | trpA | FB2170_12721 | FB2170_16311 | Cystathionine beta-synthase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.913 |
EAR00284.1 | trpB | FB2170_12721 | FB2170_09386 | Cystathionine beta-synthase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.906 |
EAR00284.1 | trpB-2 | FB2170_12721 | FB2170_16306 | Cystathionine beta-synthase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.906 |
EAR00330.1 | EAR00113.1 | FB2170_12951 | FB2170_00565 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |