node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAR00268.1 | EAR02454.1 | FB2170_12641 | FB2170_04185 | Putative hydrolase. | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | 0.641 |
EAR01537.1 | EAR02454.1 | FB2170_13453 | FB2170_04185 | Putative riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | 0.738 |
EAR01537.1 | gmk | FB2170_13453 | FB2170_04940 | Putative riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.438 |
EAR01537.1 | mnmA | FB2170_13453 | FB2170_15813 | Putative riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.553 |
EAR01537.1 | ribB | FB2170_13453 | FB2170_12556 | Putative riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Putative riboflavin biosynthesis protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
EAR01537.1 | ribH | FB2170_13453 | FB2170_09571 | Putative riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.991 |
EAR02454.1 | EAR00268.1 | FB2170_04185 | FB2170_12641 | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Putative hydrolase. | 0.641 |
EAR02454.1 | EAR01537.1 | FB2170_04185 | FB2170_13453 | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Putative riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.738 |
EAR02454.1 | EAR02455.1 | FB2170_04185 | FB2170_04190 | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Gamma-glutamyl carboxylase-like protein. | 0.827 |
EAR02454.1 | cmk | FB2170_04185 | FB2170_15298 | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Cytidylate kinase. | 0.884 |
EAR02454.1 | coaD | FB2170_04185 | FB2170_16366 | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.757 |
EAR02454.1 | gmk | FB2170_04185 | FB2170_04940 | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.617 |
EAR02454.1 | mnmA | FB2170_04185 | FB2170_15813 | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.850 |
EAR02454.1 | ribB | FB2170_04185 | FB2170_12556 | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Putative riboflavin biosynthesis protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.633 |
EAR02454.1 | ribH | FB2170_04185 | FB2170_09571 | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.776 |
EAR02454.1 | truB | FB2170_04185 | FB2170_07679 | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Putative tRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.829 |
EAR02455.1 | EAR02454.1 | FB2170_04190 | FB2170_04185 | Gamma-glutamyl carboxylase-like protein. | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | 0.827 |
cmk | EAR02454.1 | FB2170_15298 | FB2170_04185 | Cytidylate kinase. | Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | 0.884 |
cmk | coaD | FB2170_15298 | FB2170_16366 | Cytidylate kinase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.491 |
cmk | gmk | FB2170_15298 | FB2170_04940 | Cytidylate kinase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.580 |