node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NSP_11580 | NSP_14360 | NSP_11580 | NSP_14360 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutaredoxin 3 (Grx1); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.780 |
NSP_11580 | NSP_18630 | NSP_11580 | NSP_18630 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Thioredoxin reductase; Nsp18630; ORF_ID:nsp18630. | 0.810 |
NSP_11580 | NSP_42150 | NSP_11580 | NSP_42150 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Malonyl CoA-acyl carrier protein transacylase; Nsp42150; ORF_ID:nsp42150. | 0.850 |
NSP_11580 | NSP_45350 | NSP_11580 | NSP_45350 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Peptide methionine sulfoxide reductase MsrA; Nsp45350; ORF_ID:nsp45350; Belongs to the MsrA Met sulfoxide reductase family. | 0.438 |
NSP_11580 | NSP_52640 | NSP_11580 | NSP_52640 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Signal transduction histidine kinase; Nsp52640; ORF_ID:nsp52640. | 0.831 |
NSP_11580 | msrA | NSP_11580 | NSP_31490 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.509 |
NSP_11580 | panC/cmk | NSP_11580 | NSP_31610 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pantoate--beta-alanine ligase / Cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. | 0.412 |
NSP_14360 | NSP_11580 | NSP_14360 | NSP_11580 | Glutaredoxin 3 (Grx1); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.780 |
NSP_14360 | NSP_18070 | NSP_14360 | NSP_18070 | Glutaredoxin 3 (Grx1); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Putative monothiol glutaredoxin ycf64-like protein; Nsp18070; ORF_ID:nsp18070; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.688 |
NSP_14360 | NSP_18630 | NSP_14360 | NSP_18630 | Glutaredoxin 3 (Grx1); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Thioredoxin reductase; Nsp18630; ORF_ID:nsp18630. | 0.580 |
NSP_14360 | NSP_42150 | NSP_14360 | NSP_42150 | Glutaredoxin 3 (Grx1); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Malonyl CoA-acyl carrier protein transacylase; Nsp42150; ORF_ID:nsp42150. | 0.655 |
NSP_14360 | NSP_45350 | NSP_14360 | NSP_45350 | Glutaredoxin 3 (Grx1); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Peptide methionine sulfoxide reductase MsrA; Nsp45350; ORF_ID:nsp45350; Belongs to the MsrA Met sulfoxide reductase family. | 0.750 |
NSP_14360 | NSP_52640 | NSP_14360 | NSP_52640 | Glutaredoxin 3 (Grx1); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Signal transduction histidine kinase; Nsp52640; ORF_ID:nsp52640. | 0.605 |
NSP_14360 | gshB | NSP_14360 | NSP_14350 | Glutaredoxin 3 (Grx1); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Glutathione synthetase; Nsp14350; ORF_ID:nsp14350; Belongs to the prokaryotic GSH synthase family. | 0.770 |
NSP_14360 | msrA | NSP_14360 | NSP_31490 | Glutaredoxin 3 (Grx1); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.750 |
NSP_14360 | panC/cmk | NSP_14360 | NSP_31610 | Glutaredoxin 3 (Grx1); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Pantoate--beta-alanine ligase / Cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. | 0.757 |
NSP_14360 | ribBA | NSP_14360 | NSP_3810 | Glutaredoxin 3 (Grx1); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.778 |
NSP_18070 | NSP_14360 | NSP_18070 | NSP_14360 | Putative monothiol glutaredoxin ycf64-like protein; Nsp18070; ORF_ID:nsp18070; Belongs to the glutaredoxin family. Monothiol subfamily. | Glutaredoxin 3 (Grx1); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.688 |
NSP_18070 | NSP_18630 | NSP_18070 | NSP_18630 | Putative monothiol glutaredoxin ycf64-like protein; Nsp18070; ORF_ID:nsp18070; Belongs to the glutaredoxin family. Monothiol subfamily. | Thioredoxin reductase; Nsp18630; ORF_ID:nsp18630. | 0.448 |
NSP_18070 | gshB | NSP_18070 | NSP_14350 | Putative monothiol glutaredoxin ycf64-like protein; Nsp18070; ORF_ID:nsp18070; Belongs to the glutaredoxin family. Monothiol subfamily. | Glutathione synthetase; Nsp14350; ORF_ID:nsp14350; Belongs to the prokaryotic GSH synthase family. | 0.576 |