STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSP_14550Coproporphyrinogen III oxidase, aerobic; Nsp14550; ORF_ID:nsp14550. (334 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 0.887
NSP_29840
Putative membrane protein, possible involvement in cytochrome functioning/assembly; Nsp29840; ORF_ID:nsp29840.
 
  
 0.832
NSP_4750
Coproporphyrinogen III oxidase, oxygen-independent; Nsp4750; ORF_ID:nsp4750; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.604
NSP_6870
Hypothetical protein; Nsp6870; ORF_ID:nsp6870.
 
      0.597
NSP_17430
Heme chaperone HemW; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.533
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.497
hemH
Ferrochelatase, protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
   
 0.473
NSP_24540
Hypothetical protein; Nsp24540; ORF_ID:nsp24540.
   
  
 0.467
NSP_14540
Hypothetical protein; Nsp14540; ORF_ID:nsp14540.
       0.446
NSP_31770
Uroporphyrinogen-III methyltransferase / Uroporphyrinogen-III synthase; Nsp31770; ORF_ID:nsp31770; Belongs to the precorrin methyltransferase family.
     
 0.428
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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