STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSP_21780Phosphoglycerate mutase; Nsp21780; ORF_ID:nsp21780; Belongs to the phosphoglycerate mutase family. (450 aa)    
Predicted Functional Partners:
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.754
NSP_3220
Adenosylcobinamide-phosphate guanylyltransferase; Nsp3220; ORF_ID:nsp3220.
 
 
 0.716
NSP_29520
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Nsp29520; ORF_ID:nsp29520; Belongs to the UPF0284 family.
  
 
 0.693
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.683
NSP_47580
Chloride channel protein; Nsp47580; ORF_ID:nsp47580.
 
  
 0.643
pgi
Glucose-6-phosphate isomerase; Nsp18280; ORF_ID:nsp18280; Belongs to the GPI family.
    
 0.622
NSP_21790
Dihydroorotase; Nsp21790; ORF_ID:nsp21790.
    
  0.618
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
  
  
 0.614
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
    
 0.611
NSP_1410
Ribulose-phosphate 3-epimerase; Nsp1410; ORF_ID:nsp1410; Belongs to the ribulose-phosphate 3-epimerase family.
    
 0.602
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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