| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NSP_10510 | NSP_28610 | NSP_10510 | NSP_28610 | Ferredoxin-dependent glutamate synthase; Nsp10510; ORF_ID:nsp10510. | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.959 |
| NSP_10510 | NSP_42150 | NSP_10510 | NSP_42150 | Ferredoxin-dependent glutamate synthase; Nsp10510; ORF_ID:nsp10510. | Malonyl CoA-acyl carrier protein transacylase; Nsp42150; ORF_ID:nsp42150. | 0.948 |
| NSP_10510 | nadE | NSP_10510 | NSP_240 | Ferredoxin-dependent glutamate synthase; Nsp10510; ORF_ID:nsp10510. | NAD synthetase/ Glutamine amidotransferase chain of NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.935 |
| NSP_12650 | NSP_270 | NSP_12650 | NSP_270 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.926 |
| NSP_12650 | NSP_28610 | NSP_12650 | NSP_28610 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.524 |
| NSP_12650 | NSP_30820 | NSP_12650 | NSP_30820 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.419 |
| NSP_12650 | nadD | NSP_12650 | NSP_260 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase bacterial NadD family; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.907 |
| NSP_12650 | nadD-2 | NSP_12650 | NSP_47260 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase bacterial NadD family; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.904 |
| NSP_12650 | nadE | NSP_12650 | NSP_240 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | NAD synthetase/ Glutamine amidotransferase chain of NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.904 |
| NSP_12650 | nadK | NSP_12650 | NSP_39480 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.517 |
| NSP_12650 | nadK-2 | NSP_12650 | NSP_45430 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.517 |
| NSP_270 | NSP_12650 | NSP_270 | NSP_12650 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | 0.926 |
| NSP_270 | NSP_28610 | NSP_270 | NSP_28610 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.680 |
| NSP_270 | nadD | NSP_270 | NSP_260 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase bacterial NadD family; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.985 |
| NSP_270 | nadD-2 | NSP_270 | NSP_47260 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase bacterial NadD family; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.939 |
| NSP_270 | nadE | NSP_270 | NSP_240 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD synthetase/ Glutamine amidotransferase chain of NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.921 |
| NSP_28610 | NSP_10510 | NSP_28610 | NSP_10510 | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | Ferredoxin-dependent glutamate synthase; Nsp10510; ORF_ID:nsp10510. | 0.959 |
| NSP_28610 | NSP_12650 | NSP_28610 | NSP_12650 | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | 0.524 |
| NSP_28610 | NSP_270 | NSP_28610 | NSP_270 | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.680 |
| NSP_28610 | NSP_42150 | NSP_28610 | NSP_42150 | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | Malonyl CoA-acyl carrier protein transacylase; Nsp42150; ORF_ID:nsp42150. | 0.940 |