node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NSP_11580 | NSP_250 | NSP_11580 | NSP_250 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | 0.765 |
NSP_11580 | NSP_28610 | NSP_11580 | NSP_28610 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.895 |
NSP_11580 | NSP_7010 | NSP_11580 | NSP_7010 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Alkaline phosphatase; Nsp7010; ORF_ID:nsp7010. | 0.850 |
NSP_11580 | NSP_9550 | NSP_11580 | NSP_9550 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | ADP-ribose pyrophosphatase; Nsp9550; ORF_ID:nsp9550; Belongs to the Nudix hydrolase family. | 0.765 |
NSP_12650 | NSP_250 | NSP_12650 | NSP_250 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | 0.771 |
NSP_12650 | NSP_270 | NSP_12650 | NSP_270 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.886 |
NSP_12650 | NSP_7010 | NSP_12650 | NSP_7010 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Alkaline phosphatase; Nsp7010; ORF_ID:nsp7010. | 0.936 |
NSP_12650 | NSP_9550 | NSP_12650 | NSP_9550 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | ADP-ribose pyrophosphatase; Nsp9550; ORF_ID:nsp9550; Belongs to the Nudix hydrolase family. | 0.771 |
NSP_12650 | nadD | NSP_12650 | NSP_260 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase bacterial NadD family; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.899 |
NSP_12650 | nadE | NSP_12650 | NSP_240 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | NAD synthetase/ Glutamine amidotransferase chain of NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.906 |
NSP_1710 | NSP_250 | NSP_1710 | NSP_250 | Pyruvate kinase; Nsp1710; ORF_ID:nsp1710; Belongs to the pyruvate kinase family. | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | 0.776 |
NSP_1710 | NSP_28610 | NSP_1710 | NSP_28610 | Pyruvate kinase; Nsp1710; ORF_ID:nsp1710; Belongs to the pyruvate kinase family. | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.973 |
NSP_1710 | NSP_32910 | NSP_1710 | NSP_32910 | Pyruvate kinase; Nsp1710; ORF_ID:nsp1710; Belongs to the pyruvate kinase family. | Phosphoenolpyruvate synthase; Nsp32910; ORF_ID:nsp32910. | 0.888 |
NSP_1710 | NSP_9550 | NSP_1710 | NSP_9550 | Pyruvate kinase; Nsp1710; ORF_ID:nsp1710; Belongs to the pyruvate kinase family. | ADP-ribose pyrophosphatase; Nsp9550; ORF_ID:nsp9550; Belongs to the Nudix hydrolase family. | 0.776 |
NSP_250 | NSP_11580 | NSP_250 | NSP_11580 | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.765 |
NSP_250 | NSP_12650 | NSP_250 | NSP_12650 | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | 0.771 |
NSP_250 | NSP_1710 | NSP_250 | NSP_1710 | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | Pyruvate kinase; Nsp1710; ORF_ID:nsp1710; Belongs to the pyruvate kinase family. | 0.776 |
NSP_250 | NSP_270 | NSP_250 | NSP_270 | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.853 |
NSP_250 | NSP_28610 | NSP_250 | NSP_28610 | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.802 |
NSP_250 | NSP_32910 | NSP_250 | NSP_32910 | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | Phosphoenolpyruvate synthase; Nsp32910; ORF_ID:nsp32910. | 0.723 |