STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSP_25260(R)-citramalate synthase; Nsp25260; ORF_ID:nsp25260; Belongs to the alpha-IPM synthase/homocitrate synthase family. (543 aa)    
Predicted Functional Partners:
NSP_49310
3-isopropylmalate dehydratase large subunit; Nsp49310; ORF_ID:nsp49310; Belongs to the aconitase/IPM isomerase family.
 
 0.994
NSP_42420
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.909
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 0.906
NSP_28610
Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
  
 
 0.901
NSP_32970
Branched-chain amino acid aminotransferase Aminodeoxychorismate lyase; Nsp32970; ORF_ID:nsp32970.
  
 0.900
ilvD
Dihydroxy-acid dehydratase; Nsp33730; ORF_ID:nsp33730; Belongs to the IlvD/Edd family.
  
 
 0.895
NSP_20200
Acetolactate synthase small subunit; Nsp20200; ORF_ID:nsp20200.
 
 
 0.886
NSP_26730
Long-chain-fatty-acid--CoA ligase; Nsp26730; ORF_ID:nsp26730.
  
 0.873
NSP_42150
Malonyl CoA-acyl carrier protein transacylase; Nsp42150; ORF_ID:nsp42150.
  
 
 0.847
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 0.831
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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