| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NSP_12650 | NSP_250 | NSP_12650 | NSP_250 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | 0.693 |
| NSP_12650 | NSP_270 | NSP_12650 | NSP_270 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.926 |
| NSP_12650 | NSP_30820 | NSP_12650 | NSP_30820 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.419 |
| NSP_12650 | NSP_36220 | NSP_12650 | NSP_36220 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Quinolinate phosphoribosyltransferase [decarboxylating]; Nsp36220; ORF_ID:nsp36220; Belongs to the NadC/ModD family. | 0.915 |
| NSP_12650 | NSP_7010 | NSP_12650 | NSP_7010 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Alkaline phosphatase; Nsp7010; ORF_ID:nsp7010. | 0.932 |
| NSP_12650 | nadD | NSP_12650 | NSP_260 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase bacterial NadD family; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.907 |
| NSP_12650 | nadD-2 | NSP_12650 | NSP_47260 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase bacterial NadD family; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.904 |
| NSP_12650 | nadE | NSP_12650 | NSP_240 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | NAD synthetase/ Glutamine amidotransferase chain of NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.904 |
| NSP_12650 | nadK | NSP_12650 | NSP_39480 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.517 |
| NSP_12650 | nadK-2 | NSP_12650 | NSP_45430 | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.517 |
| NSP_250 | NSP_12650 | NSP_250 | NSP_12650 | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | 0.693 |
| NSP_250 | NSP_270 | NSP_250 | NSP_270 | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.854 |
| NSP_250 | NSP_7010 | NSP_250 | NSP_7010 | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | Alkaline phosphatase; Nsp7010; ORF_ID:nsp7010. | 0.717 |
| NSP_250 | nadD | NSP_250 | NSP_260 | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | Nicotinate-nucleotide adenylyltransferase bacterial NadD family; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.937 |
| NSP_250 | nadE | NSP_250 | NSP_240 | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | NAD synthetase/ Glutamine amidotransferase chain of NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.848 |
| NSP_270 | NSP_12650 | NSP_270 | NSP_12650 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family. | 0.926 |
| NSP_270 | NSP_250 | NSP_270 | NSP_250 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nudix-like transcriptional regulator NrtR; Nsp250; ORF_ID:nsp250. | 0.854 |
| NSP_270 | NSP_36220 | NSP_270 | NSP_36220 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Quinolinate phosphoribosyltransferase [decarboxylating]; Nsp36220; ORF_ID:nsp36220; Belongs to the NadC/ModD family. | 0.957 |
| NSP_270 | NSP_7010 | NSP_270 | NSP_7010 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Alkaline phosphatase; Nsp7010; ORF_ID:nsp7010. | 0.891 |
| NSP_270 | nadD | NSP_270 | NSP_260 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase bacterial NadD family; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.985 |