node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NSP_27290 | NSP_27300 | NSP_27290 | NSP_27300 | roadblock/LC7 domain family; Nsp27290; ORF_ID:nsp27290. | Hypothetical protein; Nsp27300; ORF_ID:nsp27300. | 0.999 |
NSP_27290 | NSP_27310 | NSP_27290 | NSP_27310 | roadblock/LC7 domain family; Nsp27290; ORF_ID:nsp27290. | Hypothetical protein; Nsp27310; ORF_ID:nsp27310. | 0.787 |
NSP_27300 | NSP_27290 | NSP_27300 | NSP_27290 | Hypothetical protein; Nsp27300; ORF_ID:nsp27300. | roadblock/LC7 domain family; Nsp27290; ORF_ID:nsp27290. | 0.999 |
NSP_27300 | NSP_27310 | NSP_27300 | NSP_27310 | Hypothetical protein; Nsp27300; ORF_ID:nsp27300. | Hypothetical protein; Nsp27310; ORF_ID:nsp27310. | 0.898 |
NSP_27300 | ffh | NSP_27300 | NSP_8190 | Hypothetical protein; Nsp27300; ORF_ID:nsp27300. | Signal recognition particle, subunit Ffh SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.944 |
NSP_27300 | ftsY | NSP_27300 | NSP_8720 | Hypothetical protein; Nsp27300; ORF_ID:nsp27300. | Signal recognition particle receptor protein FtsY (alpha subunit); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.995 |
NSP_27300 | rplB | NSP_27300 | NSP_43800 | Hypothetical protein; Nsp27300; ORF_ID:nsp27300. | LSU ribosomal protein L2p (L8e); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.852 |
NSP_27300 | rplC | NSP_27300 | NSP_43830 | Hypothetical protein; Nsp27300; ORF_ID:nsp27300. | LSU ribosomal protein L3p (L3e); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.852 |
NSP_27300 | rplM | NSP_27300 | NSP_43560 | Hypothetical protein; Nsp27300; ORF_ID:nsp27300. | LSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.852 |
NSP_27300 | rplN | NSP_27300 | NSP_43730 | Hypothetical protein; Nsp27300; ORF_ID:nsp27300. | LSU ribosomal protein L14p (L23e); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.865 |
NSP_27300 | rplR | NSP_27300 | NSP_43680 | Hypothetical protein; Nsp27300; ORF_ID:nsp27300. | LSU ribosomal protein L18p (L5e); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.895 |
NSP_27300 | rpmC | NSP_27300 | NSP_43750 | Hypothetical protein; Nsp27300; ORF_ID:nsp27300. | LSU ribosomal protein L29p (L35e); Nsp43750; ORF_ID:nsp43750; Belongs to the universal ribosomal protein uL29 family. | 0.865 |
NSP_27310 | NSP_27290 | NSP_27310 | NSP_27290 | Hypothetical protein; Nsp27310; ORF_ID:nsp27310. | roadblock/LC7 domain family; Nsp27290; ORF_ID:nsp27290. | 0.787 |
NSP_27310 | NSP_27300 | NSP_27310 | NSP_27300 | Hypothetical protein; Nsp27310; ORF_ID:nsp27310. | Hypothetical protein; Nsp27300; ORF_ID:nsp27300. | 0.898 |
ffh | NSP_27300 | NSP_8190 | NSP_27300 | Signal recognition particle, subunit Ffh SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Hypothetical protein; Nsp27300; ORF_ID:nsp27300. | 0.944 |
ffh | ftsY | NSP_8190 | NSP_8720 | Signal recognition particle, subunit Ffh SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Signal recognition particle receptor protein FtsY (alpha subunit); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.990 |
ffh | rplB | NSP_8190 | NSP_43800 | Signal recognition particle, subunit Ffh SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | LSU ribosomal protein L2p (L8e); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.962 |
ffh | rplC | NSP_8190 | NSP_43830 | Signal recognition particle, subunit Ffh SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | LSU ribosomal protein L3p (L3e); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.964 |
ffh | rplM | NSP_8190 | NSP_43560 | Signal recognition particle, subunit Ffh SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | LSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.963 |
ffh | rplN | NSP_8190 | NSP_43730 | Signal recognition particle, subunit Ffh SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | LSU ribosomal protein L14p (L23e); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.962 |