STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSP_31240Single-stranded-DNA-specific exonuclease RecJ; Nsp31240; ORF_ID:nsp31240. (780 aa)    
Predicted Functional Partners:
NSP_27460
Single-stranded-DNA-specific exonuclease RecJ; Nsp27460; ORF_ID:nsp27460.
  
  
 
0.693
priA
Helicase PriA essential for oriC/DnaA-independent DNA replication; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
     0.649
NSP_31480
Putative cyanobacterial membrane protein, in cluster with PxcA; Nsp31480; ORF_ID:nsp31480.
 
   
 0.631
NSP_31220
Superfamily I DNA and RNA helicase; Nsp31220; ORF_ID:nsp31220.
 
    0.610
NSP_45750
ATP-dependent DNA helicase UvrD/PcrA/Rep; Nsp45750; ORF_ID:nsp45750.
 
   
 0.571
NSP_80
Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake; Nsp80; ORF_ID:nsp80.
 
   
 0.568
pheT
Phenylalanyl-tRNA synthetase beta chain; Nsp15080; ORF_ID:nsp15080; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
    0.567
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
    
 
 0.564
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
   
 0.561
NSP_14050
Competence protein; Nsp14050; ORF_ID:nsp14050.
 
   
 0.560
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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