Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (351 aa)    
Predicted Functional Partners:
NSP_43120
Sulfur carrier protein adenylyltransferase ThiF; Nsp43120; ORF_ID:nsp43120.
    
 0.913
mnmE
GTPase and tRNA-U34 5-formylation enzyme TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 
 0.908
mnmG
tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
  
 0.901
NSP_45540
GMP synthase [glutamine-hydrolyzing]; Nsp45540; ORF_ID:nsp45540.
    
 0.764
NSP_28130
Cysteine desulfurase; Nsp28130; ORF_ID:nsp28130.
  
 
 0.755
NSP_6340
Cysteine desulfurase; Nsp6340; ORF_ID:nsp6340; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.755
NSP_37340
Cysteine desulfurase; Nsp37340; ORF_ID:nsp37340.
  
 
 0.748
NSP_40680
Cysteine desulfurase, NifS subfamily; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
  
 
 0.748
NSP_53270
Sulfur carrier protein ThiS; Nsp53270; ORF_ID:nsp53270.
   
 
  0.739
NSP_3570
Sulfur acceptor protein SufE for iron-sulfur cluster assembly; Nsp3570; ORF_ID:nsp3570.
     
 0.720
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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