node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NSP_32260 | queE | NSP_32260 | NSP_32270 | Undecaprenyl-phosphate galactosephosphotransferase; Nsp32260; ORF_ID:nsp32260; Belongs to the anti-sigma-factor antagonist family. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.477 |
NSP_46080 | NSP_51210 | NSP_46080 | NSP_51210 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Nsp46080; ORF_ID:nsp46080. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.996 |
NSP_46080 | queE | NSP_46080 | NSP_32270 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Nsp46080; ORF_ID:nsp46080. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.424 |
NSP_51210 | NSP_46080 | NSP_51210 | NSP_46080 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Nsp46080; ORF_ID:nsp46080. | 0.996 |
NSP_51210 | NSP_8980 | NSP_51210 | NSP_8980 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 6-pyruvoyl tetrahydrobiopterin synthase; Nsp8980; ORF_ID:nsp8980. | 0.700 |
NSP_51210 | queE | NSP_51210 | NSP_32270 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.423 |
NSP_8980 | NSP_51210 | NSP_8980 | NSP_51210 | 6-pyruvoyl tetrahydrobiopterin synthase; Nsp8980; ORF_ID:nsp8980. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.700 |
NSP_8980 | guaA | NSP_8980 | NSP_48730 | 6-pyruvoyl tetrahydrobiopterin synthase; Nsp8980; ORF_ID:nsp8980. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.430 |
NSP_8980 | queC | NSP_8980 | NSP_25480 | 6-pyruvoyl tetrahydrobiopterin synthase; Nsp8980; ORF_ID:nsp8980. | Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.947 |
NSP_8980 | queE | NSP_8980 | NSP_32270 | 6-pyruvoyl tetrahydrobiopterin synthase; Nsp8980; ORF_ID:nsp8980. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.978 |
NSP_8980 | queF | NSP_8980 | NSP_28540 | 6-pyruvoyl tetrahydrobiopterin synthase; Nsp8980; ORF_ID:nsp8980. | NADPH dependent preQ0 reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.891 |
glmS | guaA | NSP_27630 | NSP_48730 | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.495 |
glmS | purF | NSP_27630 | NSP_52200 | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.697 |
glmS | queC | NSP_27630 | NSP_25480 | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.584 |
glmS | queE | NSP_27630 | NSP_32270 | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.546 |
glmS | queF | NSP_27630 | NSP_28540 | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | NADPH dependent preQ0 reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.432 |
guaA | NSP_8980 | NSP_48730 | NSP_8980 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 6-pyruvoyl tetrahydrobiopterin synthase; Nsp8980; ORF_ID:nsp8980. | 0.430 |
guaA | glmS | NSP_48730 | NSP_27630 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.495 |
guaA | purF | NSP_48730 | NSP_52200 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.795 |
guaA | queE | NSP_48730 | NSP_32270 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.442 |