node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NSP_11420 | NSP_34120 | NSP_11420 | NSP_34120 | Nsp11420; ORF_ID:nsp11420; Belongs to the ClpA/ClpB family. | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | 0.665 |
NSP_11420 | NSP_38080 | NSP_11420 | NSP_38080 | Nsp11420; ORF_ID:nsp11420; Belongs to the ClpA/ClpB family. | 16.6 kDa small heat shock protein molecular chaperon; Nsp38080; ORF_ID:nsp38080; Belongs to the small heat shock protein (HSP20) family. | 0.863 |
NSP_11420 | NSP_3970 | NSP_11420 | NSP_3970 | Nsp11420; ORF_ID:nsp11420; Belongs to the ClpA/ClpB family. | Chaperone protein HtpG; Nsp3970; ORF_ID:nsp3970. | 0.771 |
NSP_23650 | NSP_38080 | NSP_23650 | NSP_38080 | Hypothetical protein; Nsp23650; ORF_ID:nsp23650. | 16.6 kDa small heat shock protein molecular chaperon; Nsp38080; ORF_ID:nsp38080; Belongs to the small heat shock protein (HSP20) family. | 0.866 |
NSP_23650 | NSP_3970 | NSP_23650 | NSP_3970 | Hypothetical protein; Nsp23650; ORF_ID:nsp23650. | Chaperone protein HtpG; Nsp3970; ORF_ID:nsp3970. | 0.838 |
NSP_34120 | NSP_11420 | NSP_34120 | NSP_11420 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Nsp11420; ORF_ID:nsp11420; Belongs to the ClpA/ClpB family. | 0.665 |
NSP_34120 | NSP_38080 | NSP_34120 | NSP_38080 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | 16.6 kDa small heat shock protein molecular chaperon; Nsp38080; ORF_ID:nsp38080; Belongs to the small heat shock protein (HSP20) family. | 0.540 |
NSP_34120 | NSP_3970 | NSP_34120 | NSP_3970 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Chaperone protein HtpG; Nsp3970; ORF_ID:nsp3970. | 0.768 |
NSP_34120 | NSP_47790 | NSP_34120 | NSP_47790 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Nsp47790; ORF_ID:nsp47790; Belongs to the ClpA/ClpB family. | 0.665 |
NSP_34120 | clpB | NSP_34120 | NSP_3930 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.665 |
NSP_34120 | clpB-2 | NSP_34120 | NSP_41610 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.665 |
NSP_38080 | NSP_11420 | NSP_38080 | NSP_11420 | 16.6 kDa small heat shock protein molecular chaperon; Nsp38080; ORF_ID:nsp38080; Belongs to the small heat shock protein (HSP20) family. | Nsp11420; ORF_ID:nsp11420; Belongs to the ClpA/ClpB family. | 0.863 |
NSP_38080 | NSP_23650 | NSP_38080 | NSP_23650 | 16.6 kDa small heat shock protein molecular chaperon; Nsp38080; ORF_ID:nsp38080; Belongs to the small heat shock protein (HSP20) family. | Hypothetical protein; Nsp23650; ORF_ID:nsp23650. | 0.866 |
NSP_38080 | NSP_34120 | NSP_38080 | NSP_34120 | 16.6 kDa small heat shock protein molecular chaperon; Nsp38080; ORF_ID:nsp38080; Belongs to the small heat shock protein (HSP20) family. | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | 0.540 |
NSP_38080 | NSP_38090 | NSP_38080 | NSP_38090 | 16.6 kDa small heat shock protein molecular chaperon; Nsp38080; ORF_ID:nsp38080; Belongs to the small heat shock protein (HSP20) family. | Putative membrane protein; Nsp38090; ORF_ID:nsp38090. | 0.693 |
NSP_38080 | NSP_38100 | NSP_38080 | NSP_38100 | 16.6 kDa small heat shock protein molecular chaperon; Nsp38080; ORF_ID:nsp38080; Belongs to the small heat shock protein (HSP20) family. | Protein-L-isoaspartate O-methyltransferase; Nsp38100; ORF_ID:nsp38100. | 0.723 |
NSP_38080 | NSP_3970 | NSP_38080 | NSP_3970 | 16.6 kDa small heat shock protein molecular chaperon; Nsp38080; ORF_ID:nsp38080; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein HtpG; Nsp3970; ORF_ID:nsp3970. | 0.819 |
NSP_38080 | NSP_47790 | NSP_38080 | NSP_47790 | 16.6 kDa small heat shock protein molecular chaperon; Nsp38080; ORF_ID:nsp38080; Belongs to the small heat shock protein (HSP20) family. | Nsp47790; ORF_ID:nsp47790; Belongs to the ClpA/ClpB family. | 0.863 |
NSP_38080 | clpB | NSP_38080 | NSP_3930 | 16.6 kDa small heat shock protein molecular chaperon; Nsp38080; ORF_ID:nsp38080; Belongs to the small heat shock protein (HSP20) family. | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.863 |
NSP_38080 | clpB-2 | NSP_38080 | NSP_41610 | 16.6 kDa small heat shock protein molecular chaperon; Nsp38080; ORF_ID:nsp38080; Belongs to the small heat shock protein (HSP20) family. | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.863 |