STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menH2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC); Belongs to the AB hydrolase superfamily. MenH family. (281 aa)    
Predicted Functional Partners:
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
  0.989
NSP_26730
Long-chain-fatty-acid--CoA ligase; Nsp26730; ORF_ID:nsp26730.
  
 0.982
NSP_26720
Malonyl CoA-acyl carrier protein transacylase; Nsp26720; ORF_ID:nsp26720.
  
 0.960
NSP_42150
Malonyl CoA-acyl carrier protein transacylase; Nsp42150; ORF_ID:nsp42150.
  
 0.936
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
  
  0.906
NSP_26950
Long-chain-fatty-acid--CoA ligase; Nsp26950; ORF_ID:nsp26950.
   
 0.887
NSP_48210
O-succinylbenzoate-CoA synthase; Nsp48210; ORF_ID:nsp48210; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
  
  0.858
NSP_50530
Long-chain-fatty-acid--CoA ligase; Nsp50530; ORF_ID:nsp50530.
   
 0.840
NSP_42160
Malonyl CoA-acyl carrier protein transacylase; Nsp42160; ORF_ID:nsp42160.
  
 0.839
NSP_26920
Long-chain-fatty-acid--CoA ligase; Nsp26920; ORF_ID:nsp26920.
   
 0.800
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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