STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSP_46920DNA polymerase III delta subunit; Nsp46920; ORF_ID:nsp46920. (331 aa)    
Predicted Functional Partners:
NSP_20
DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.992
NSP_18930
DNA polymerase III delta prime subunit; Nsp18930; ORF_ID:nsp18930.
  
 
 0.986
dnaX
DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.985
NSP_19350
Amino-terminal intein-mediated trans-splice / DNA polymerase III alpha subunit; Nsp19350; ORF_ID:nsp19350.
   
 0.972
NSP_45290
DNA polymerase III alpha subunit / Carboxy-terminal intein-mediated trans-splice; Nsp45290; ORF_ID:nsp45290.
   
 0.972
NSP_30300
DNA polymerase III delta prime subunit; Nsp30300; ORF_ID:nsp30300.
   
 0.966
NSP_22320
Putative DNA polymerase III, epsilon subunit; Nsp22320; ORF_ID:nsp22320.
    
 0.920
NSP_10410
Hypothetical protein; Nsp10410; ORF_ID:nsp10410.
 
  
 0.696
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
     
 0.694
NSP_38280
Phytochrome-like protein; Nsp38280; ORF_ID:nsp38280.
 
  
  0.678
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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