STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSP_51420FKBP-type peptidyl-prolyl cis-trans isomerase; Nsp51420; ORF_ID:nsp51420. (162 aa)    
Predicted Functional Partners:
NSP_3970
Chaperone protein HtpG; Nsp3970; ORF_ID:nsp3970.
   
 0.986
NSP_35040
Hypothetical protein; Nsp35040; ORF_ID:nsp35040.
    
 0.925
NSP_46790
Serine/threonine kinase; Nsp46790; ORF_ID:nsp46790.
    
 0.925
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
    
  0.895
NSP_10340
Hypothetical protein; Nsp10340; ORF_ID:nsp10340.
    
 0.869
NSP_23340
Hypothetical protein; Nsp23340; ORF_ID:nsp23340.
    
 0.869
NSP_32510
Hypothetical protein; Nsp32510; ORF_ID:nsp32510.
    
 0.869
NSP_42250
Hypothetical protein; Nsp42250; ORF_ID:nsp42250.
    
 0.869
infA
Translation initiation factor 1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.858
NSP_22510
Hypothetical protein; Nsp22510; ORF_ID:nsp22510.
    
 0.853
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.