Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NSP_7010Alkaline phosphatase; Nsp7010; ORF_ID:nsp7010. (1951 aa)    
Predicted Functional Partners:
NSP_6490
Glycerophosphoryl diester phosphodiesterase; Nsp6490; ORF_ID:nsp6490.
 
 0.977
NSP_35720
Putative purple acid phosphatase precursor; Nsp35720; ORF_ID:nsp35720.
    
 0.958
cpdA
3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
    
 0.958
panC/cmk
Pantoate--beta-alanine ligase / Cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family.
   
  0.947
pyrE
Orotidine 5'-phosphate decarboxylase / Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
    
 0.933
NSP_12650
Competence/damage-inducible protein CinA; Nsp12650; ORF_ID:nsp12650; Belongs to the CinA family.
  
 
 0.932
NSP_29000
Inosine-5'-monophosphate dehydrogenase; Nsp29000; ORF_ID:nsp29000.
   
 0.932
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.923
NSP_10510
Ferredoxin-dependent glutamate synthase; Nsp10510; ORF_ID:nsp10510.
    
 0.912
NSP_41860
Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
 
  
  0.910
Your Current Organism:
Nodularia spumigena
NCBI taxonomy Id: 313624
Other names: N. spumigena CCY9414, Nodularia spumigena CCY9414
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